Specificity
Each conjugate comprises antigen covalently bound to horseradish peroxide and is suitable as a tracer in immunoassay development.
Alternative Names
N-Acetylglucosamine; NAG; N-acetyl-D-glucosamine; GlcNAc; 2-(Acetylamino)-2-deoxy-D-glucose; N-Acetyl-D-Glucosamine
Format
The conjugate is supplied as a concentrate. Dilute as required and use working strength conjugate immediately after dilution
Storage
2 - 8°C for up to 3 months / -20°C for long term storage
Introduction
N-Acetylglucosamine (N-acetyl-D-glucosamine, or GlcNAc, or NAG) is a monosaccharide and a derivative of glucose. It is an amide between glucosamine and acetic acid. It has a molecular formula of C8H15NO6, a molar mass of 221.21 g/mol, and it is significant in several biological systems. It is part of a biopolymer in the bacterial cell wall, built from alternating units of GlcNAc and N-acetylmuramic acid (MurNAc), cross-linked with oligopeptides at the lactic acid residue of MurNAc. This layered structure is called peptidoglycan (formerly called murein). GlcNAc is the monomeric unit of the polymer chitin, which forms the outer coverings of insects and crustaceans. It is the main component of the radulas of mollusks, the beaks of cephalopods, and a major component of the cell walls of most fungi.
Citations
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Bottone, FG; Martinez, JM; et al. Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells. CARCINOGENESIS 25:349-357(2004).
Kumar, A; Nevill, G; et al. A comparative study of gland cells implicated in the nerve dependence of salamander limb regeneration. JOURNAL OF ANATOMY 217:16-25(2010).