Anti-TXN monoclonal antibody, clone 7D21

Antibody Isotype

IgG1

Clone

7D21

Species Reactivity

Human

Immunogen

TXN (AAH03377, 1 a.a. ~ 106 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

thioredoxin; ATL-derived factor; TRX; DKFZp686B1993; Surface-associated sulphydryl protein; MGC61975; ADF; TRDX; SASP; TRX1; OTTHUMP00000021892; OTTHUMP00000021893

Entrez Gene ID

UniProt ID

Antigen Description

Thioredoxin is a 12-kD oxidoreductase enzyme containing a dithiol-disulfide active site. It is ubiquitous and found in many organisms from plants and bacteria to mammals. Multiple in vitro substrates for thioredoxin have been identified, including ribonuclease, choriogonadotropins, coagulation factors, glucocorticoid receptor, and insulin. Reduction of insulin is classically used as an activity test.
Mouse monoclonal antibody raised against a partial recombinant TXN.

Pathway

Folic Acid Network, organism-specific biosystem; Folic Acid Network, organism-specific biosystem; Immune System, organism-specific biosystem; Inflammasomes, organism-specific biosystem; Innate Immunity Signaling, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem