Anti-TNFRSF9 monoclonal antibody (CABT-23986MH)

Mouse Anti-Human TNFRSF9 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgM
Clone
T27
Species Reactivity
Human
Immunogen
Recombinant protein corresponding to a 140 amino acid fragment from external region at N-terminus of human TNFRSF9.
Conjugate
Unconjugated

Applications


Application Notes
Immunohistochemistry (1:40-1:80) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
tumor necrosis factor receptor superfamily, member 9; FLJ43501; CD137; MGC2172; ILA; homolog of mouse 4-1BB
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem

Citations


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References


Fisher, TS; Kamperschroer, C; et al. Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity. CANCER IMMUNOLOGY IMMUNOTHERAPY 61:1721-1733(2012).
Zhou, HW; DeLoid, G; et al. Genome-Wide RNAi Screen in IFN-gamma-Treated Human Macrophages Identifies Genes Mediating Resistance to the Intracellular Pathogen Francisella tularensis. PLOS ONE 7:-(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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