Anti-HBG1 monoclonal antibody

Antibody Isotype

IgG2a

Clone

2H9

Species Reactivity

Human

Immunogen

HBG1 (AAH10914, 1 a.a. ~ 148 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Unconjugated

Alternative Names

hemoglobin, gamma A; A-gamma globin; Hb F Agamma; gamma A hemoglobin; Hemoglobin gamma-1 chain; gamma globin; Hemoglobin gamma-A chain; gamma-1-globin; HBGA; hemoglobin subunit gamma-1; HBGR; hemoglobin, gamma, regulator of; HSGGL1; PRO2979; OTTHUMP000000

Entrez Gene ID

3047

UniProt ID

D9YZU8

Antigen Description

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5"-epsilon -- gamma-G -- gamma-A -- delta -- beta--3".
Mouse monoclonal antibody raised against a full-length recombinant HBG1.

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More