Anti-C21ORF2 monoclonal antibody (CABT-10321MH)
Mouse anti-Human C21ORF2 monoclonal antibody for sELISA, ELISA
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C21orf2 (NP_004919, 1 a.a. ~ 102 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
chromosome 21 open reading frame 2; hypothetical protein LOC755; A2; C21orf-HUMF09G8.5; YF5; YF5/A2
C21orf2 (Chromosome 21 Open Reading Frame 2) is a Protein Coding gene. Diseases associated with C21orf2 include st. louis encephalitis. Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.
Mouse monoclonal antibody raised against a partial recombinant C21orf2. May play roles in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. The function about C21ORF2 antigen include molecular_function.
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Kahler, CM; Carlson, RW; et al. Inner core biosynthesis of lipooligosaccharide (LOS) in Neisseria meningitidis serogroup B: Identification and role in LOS assembly of the alpha 1,2 N-acetylglucosamine transferase (RfaK). JOURNAL OF BACTERIOLOGY 178:1265-1273(1996).
Boese, A; Sauter, M; et al. Human endogenous retrovirus protein cORF supports cell transformation and associates with the promyelocytic leukemia zinc finger protein. ONCOGENE 19:4328-4336(2000).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.