Anti-C21ORF2 monoclonal antibody (CABT-10321MH)


Host Species
Antibody Isotype
Species Reactivity
C21orf2 (NP_004919, 1 a.a. ~ 102 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.


Alternative Names
chromosome 21 open reading frame 2; hypothetical protein LOC755; A2; C21orf-HUMF09G8.5; YF5; YF5/A2
Entrez Gene ID
UniProt ID

Product Background

Gene summary
C21orf2 (Chromosome 21 Open Reading Frame 2) is a Protein Coding gene. Diseases associated with C21orf2 include st. louis encephalitis. Four alternatively spliced transcript variants encoding four different isoforms have been found for this nuclear gene. All isoforms contain leucine-rich repeats. Three of these isoforms are mitochondrial proteins and one of them lacks the target peptide, so is not located in mitochondrion. This gene is down-regulated in Down syndrome (DS) brain, which may represent mitochondrial dysfunction in DS patients.
Antigen Description

Mouse monoclonal antibody raised against a partial recombinant C21orf2. May play roles in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. The function about C21ORF2 antigen include molecular_function.


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Jager, D; Stockert, E; et al. Identification of a tissue-specific putative transcription factor in breast tissue by serological screening of a breast cancer library. CANCER RESEARCH 61:2055-2061(2001).
Muneta, Y; Kikuma, R; et al. Molecular cloning, chromosomal location, and biological activity of porcine interleukin-21. JOURNAL OF VETERINARY MEDICAL SCIENCE 66:269-275(2004).

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