Mitochondrial Antigen (DAG-T1243)


Online Inquiry Add to basket

Product Overview
Purified from bovine heart muscle. After coating onto ELISA plates the product will bind autoantibodies to mitochondrial antigen.
The mitochondrial antigen (5 subunits: PDH E2 (74 kDa), PDH E3 (Protein X, 56 kDa), PDH E3 (lipoamide dehydrogenase, 55 kDa), PDH E1α (41 kDa) and PDH E1β (36 kDa)) is more than 90% pure, as assessed by SDS polyacrylamide gel electrophoresis.
0.1-1.0 mg/ml
0.20 mg
The product is stabilised with 0.1% Micr-O-protect TM and 20% glycerol. Store at -20°C or below (long term) or at +4°C (short term). Avoid repeated freezing and thawing. Mix thoroughly before use.
The mitochondrion (plural mitochondria) is a membrane bound organelle found in most eukaryotic cells (the cells that make up plants, animals, fungi, and many other forms of life). The word mitochondrion comes from the Greek μ?το?, mitos, i.e. "thread", and χονδρ?ον, chondrion, i.e. "granule".
Mitochondria range from 0.5 to 1.0 micrometer (μm) in diameter. These structures are sometimes described as "cellular power plants" because they generate most of the cell's supply of adenosine triphosphate (ATP), used as a source of chemical energy. In addition to supplying cellular energy, mitochondria are involved in other tasks such as signaling, cellular differentiation, cell death, as well as the control of the cell cycle and cell growth. Mitochondria have been implicated in several human diseases, including mitochondrial disorders and cardiac dysfunction, and may play a role in the aging process. More recent research indicates that autism, especially severe autism, is correlated with mitochondrial defects.
Several characteristics make mitochondria unique. The number of mitochondria in a cell can vary widely by organism, tissue, and cell type. For instance, red blood cells have no mitochondria, whereas liver cells can have more than 2000. The organelle is composed of compartments that carry out specialized functions. These compartments or regions include the outer membrane, the intermembrane space, the inner membrane, and the cristae and matrix. Mitochondrial proteins vary depending on the tissue and the species. In humans, 615 distinct types of proteins have been identified from cardiac mitochondria, whereas in rats, 940 proteins have been reported. The mitochondrial proteome is thought to be dynamically regulated. Although most of a cell's DNA is contained in the cell nucleus, the mitochondrion has its own independent genome. Further, its DNA shows substantial similarity to bacterial genomes.
Mitochondrion;Mitochondrial Antigen;


Have you cited DAG-T1243 in a publication? Let us know and earn a reward for your research.

Customer Reviews

Write a review, share your experiences with others and get rewarded !

Online Inquiry

Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Mitochondrial Antigen

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket