Product Overview
Blocking peptide for anti-39148 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
Antigen Description
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010]
Function
MHC class II protein binding; ubiquitin-protein ligase activity; zinc ion binding;
Synonyms
MARCH8; membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase; MIR; c-MIR; RNF178; MARCH-VIII; E3 ubiquitin-protein ligase MARCH8; RING finger protein 178; membrane-associated RING-CH protein VIII; membrane-associated RING finger protein 8; c-mir, cellular modulator of immune recognition; cellular modulator of immune recognition (c-MIR);
Citations
Publication ()
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COA
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