L. monocytogenes Flagellin [His] (DAG-H10322)

L. monocytogenes Flagellin [His], recombinant protein from E. coli Datasheet

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Nature
Recombinant
Tag/Conjugate
His
Purity
> 95 % as determined by SDS-PAGE
Size
10μg; 20μg
Storage
Store it under sterile conditions at -70 °C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Introduction
Flagellin (FliC) is a subunit protein that polymerizes (along with other proteins) to form the filaments of bacterial flagella. Assembly of the bacterial flagellum occurs in a precise, temporal order where the basal component (FlgE, FlgK, and FlgL are assembled inside the bacterial membrane, followed by exportation of the filament cap protein FliD, and secretion of about 20,000 flagellin monomers (FliC) through the channel. FliC monomers are polymerized to form the tail filament. FliC monomers can function as pathogen-associated molecular patterns (PAMPs), and can be detected by host cells through surface-localized toll-like receptor6(TLR5) and cytosolic Nod-like receptors (NLRs).
Keywords
41 kDa antigen; flaF; Flagellar filament 41 kDa core protein; fliC; hag; P41; Flagellin; FliC

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