Human LRP5 blocking peptide (CDBP1782)

Synthetic Human LRP5 blocking peptide for Apuri, BL, ELISA Datasheet

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Product Overview
Blocking/Immunizing peptide for anti-LRP5 antibody
Species Reactivity
Human, Mouse, Rat
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Lyophilized powder
100 μg
Shipped at ambient temperature, store at -20°C.
UniProt ID
Antigen Description
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Wnt-activated receptor activity; Wnt-protein binding; coreceptor activity; protein binding; receptor activity; NOT toxin transporter activity;
LRP5; low density lipoprotein receptor-related protein 5; EVR1, exudative vitreoretinopathy 1 , LRP7, OPPG, osteoporosis pseudoglioma syndrome; low-density lipoprotein receptor-related protein 5; BMND1; HBM; LR3; OPS; LRP-5; low density lipoprotein receptor-related protein 7; EVR1; EVR4; LRP7; OPPG; OPTA1; VBCH2;


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