Human SH2B3 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-LNK/SH2B3 antibody

Target

LNK / SH2B3

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]

Function

signal transducer activity;

Synonyms

SH2B3; SH2B adaptor protein 3; SH2B adapter protein 3; IDDM20; LNK; lymphocyte adaptor protein; signal transduction protein Lnk; lymphocyte-specific adapter protein Lnk;