Blocking/Immunizing peptide for anti-LNK/SH2B3 antibody
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
signal transducer activity;
SH2B3; SH2B adaptor protein 3; SH2B adapter protein 3; IDDM20; LNK; lymphocyte adaptor protein; signal transduction protein Lnk; lymphocyte-specific adapter protein Lnk;