Human PAFAH1B1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-LIS1/PAFAH1B1 antibody

Target

LIS1 / PAFAH1B1

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This locus was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. This gene encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq, Apr 2009]

Function

dynactin binding; dynein binding; dynein intermediate chain binding; heparin binding; microtubule binding; phospholipase binding; phosphoprotein binding; protein binding; protein homodimerization activity;

Synonyms

PAFAH1B1; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa); MDS; LIS1; LIS2; MDCR; PAFAH; platelet-activating factor acetylhydrolase IB subunit alpha; LIS-1; PAFAH alpha; PAF-AH alpha; PAF-AH 45 kDa subunit; lissencephaly 1 protein; lissencephaly-1 protein; PAF acetylhydrolase 45 kDa subunit; platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa); platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD);