KLK2 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

KLK2 peptide corresponds to 14 amino acids of KLK2.

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Preservative: None Constituents: 0.001% Tween 20, 150M Sodium chloride, 30mM HEPES, 2mM EDTA, pH 6.75

Reconstitution

KLK2 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]

Entrez Gene ID

Synonyms

KLK2; kallikrein-related peptidase 2; hK2; hGK-1; KLK2A2; kallikrein-2; tissue kallikrein-2; glandular kallikrein 2; glandular kallikrein-1; kallikrein 2, prostatic;