Human KCNQ3 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-KCNQ3 antibody

Target

KCNQ3

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]

Function

potassium channel activity; voltage-gated ion channel activity; voltage-gated potassium channel activity;

Synonyms

KCNQ3; potassium voltage-gated channel, KQT-like subfamily, member 3; EBN2; potassium voltage-gated channel subfamily KQT member 3; Kv7.3; potassium channel subunit alpha KvLQT3; voltage-gated potassium channel subunit Kv7.3; potassium channel, voltage-gated, subfamily Q, member 3; BFNC2; KV7.3; FLJ37386; FLJ38392; DKFZp686C0248;