Human IRF1 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the IRF family.Contains 1 IRF tryptophan pentad repeat DNA-binding domain.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq, Jul 2008]

Function

DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; protein binding; sequence-specific DNA binding transcription factor activity;

Synonyms

IRF1; interferon regulatory factor 1; MAR; IRF-1; interferon regulatory factor 1 isoform d78;