This gene encodes a subunit of the chromatin remodeling complex, which is classified into subfamilies depending on sequence features apart from the conserved ATPase domain. This protein is the catalytic ATPase subunit of the INO80 chromatin remodeling complex, which is characterized by a DNA-binding domain. This protein is proposed to bind DNA and be recruited by the YY1 transcription factor to activate certain genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Function
ATP binding; ATPase activity; DNA binding; DNA helicase activity; actin binding; alpha-tubulin binding; protein binding;
Synonyms
INO80; INO80 complex subunit; INOC1; INO80A; hINO80; DNA helicase INO80; INO80 homolog; homolog of yeast INO80; INO80 complex subunit A; putative DNA helicase INO80 complex homolog 1;
Citations
Publication ()
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