SARS Nucleocapsid (DAG-P2160)

SARS Nucleocapsid (aa 1 - 352), recombinant protein from E. coli

Product Overview
Human coronavirus SARS Nucleocapsid Protein protein fragment
Nature
Recombinant
Tag/Conjugate
Unconjugated
Molecular Weight
5 kDa
Cellular Localization
Inside the virion, complexed with the viral RNA. May be associated with cellular membranes where it participates in viral RNA synthesis and virus budding.
Procedure
None
Purity
> 95 % by SDS-PAGE.
Format
Liquid
Buffer
Constituents: 49% Tris buffered saline, 50% Glycerol
Preservative
None
Storage
Store at +4°C or -20°C long term. Avoid repeated freeze / thaw cycles. Store undiluted. Constituents: 49% Tris buffered saline, 50% Glycerol
Introduction
Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the SARS coronavirus (SARS-CoV). Between November 2002 and July 2003, an outbreak of SARS in southern China caused an eventual 8,273 cases and 775 deaths
Antigen Description
The nucleocapsid protein of SARS shares little homology with nucleocapsid proteins of other members of the coronavirus family. Nucleocapsid proteins of other coronavirus have been reported to be involved in forming the viral core and also in the packaging and transcription of the viral RNA.
Keywords
N; NC; Nucleocapsid protein; Nucleoprotein; Protein N; SARS coronavirus N protein; SARS CoV; CoV N protein

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References


Shi, SQ; Peng, JP; et al. The expression of membrane protein augments the specific responses induced by SARS-CoV nucleocapsid DNA immunization. MOLECULAR IMMUNOLOGY 43:1791-1798(2006).
Lau, SKP; Woo, PCY; et al. Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102:14040-14045(2005).

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