Anti-HTT monoclonal antibody (DMABT-H13898)

Mouse anti-Human HTT monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
4G2
Species Reactivity
Human
Immunogen
HD (NP_002102, 81 a.a. ~ 190 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
HTT; huntingtin; HD, huntingtin (Huntington disease); IT15; huntington disease protein; HD
Entrez Gene ID
UniProt ID

Product Background


Pathway
Direct p53 effectors, organism-specific biosystem;FHGS2Signaling Pathway, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem;

Citations


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References


Cho, KJ; Lee, BI; et al. INHIBITION OF APOPTOSIS SIGNAL-REGULATING KINASE 1 REDUCES ENDOPLASMIC RETICULUM STRESS AND NUCLEAR HUNTINGTIN FRAGMENTS IN A MOUSE MODEL OF HUNTINGTON DISEASE. NEUROSCIENCE 163:1128-1134(2009).
Ehrnhoefer, DE; Duennwald, M; et al. Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. HUMAN MOLECULAR GENETICS 15:2743-2751(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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