Anti-HSD3B1 monoclonal antibody (DMABT-H13970)

Mouse anti-Human HSD3B1 monoclonal antibody for WB, IHC, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4D22-E5
Species Reactivity
Human
Immunogen
HSD3B1 (AAH31999.1,2a.a. ~ 373 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
HSD3B1; hydroxy-delta-5-steroid dehydrogenase,4beta- and steroid delta-isomerase 1; HSD3B, HSDB3; 4beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; SDR11E1; short chain dehydrogenase/reductase family 11E
Entrez Gene ID
UniProt ID

Product Background


Pathway
Androgen biosynthesis, organism-specific biosystem; C19/C18-Steroid hormone biosynthesis, pregnenolone =>androstenedione =>estrone, organism-specific biosystem; C19/C18-Steroid hormone biosynthesis, pregnenolone =>androstenedione =>estrone, conserved biosystem;

Citations


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References


Foti, DN; Reichardt, JK; et al. YY1 binding within the human HSD3132 gene intron 1 is required for maximal basal promoter activity: Identification of YY1 as the 3 beta 1-A factor. JOURNAL OF MOLECULAR ENDOCRINOLOGY 33:99-119(2004).
Nordenstroem, A; Forest, MG; et al. A case of 3 beta-hydroxysteroid dehydrogenase type II (HSD3B2) deficiency picked up by neonatal screening for 21-hydroxylase deficiency: Difficulties and delay in etiologic diagnosis. HORMONE RESEARCH 68:204-208(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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