HIV type 2 (DAG4427)

HIV type 2, recombinant protein from E. coli Datasheet

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Product Overview
Recombinant HIV-II Antigen (rHIV-II)
Nature
Recombinant
Tag/Conjugate
Unconjugated
Purity
Greater than 98.0%
Format
Sterile-filtered white lyophilized (freeze-dried) powder.The protein has been lyophilized after extensive dialysis against 5 mM phosphat buffer (pH=7.3) containing 0.01% SDS.
Concentration
Protein quantitation was carried out by two independant methods: 1. UV spectroscopy at 280 nm using the absorbancy value of 3.14 as the extinction coefficient for a 0.1% (1 mg/ml) solution. This value was calculated by using the PC GENE computer analysi
Storage
2-8°C short term, -20°C long term
Introduction
One of the obstacles to treatment of the human immunodeficiency virus is its high genetic variability. HIV can be divided into two major types, HIV type 1 (HIV-1) and HIV type 2 (HIV-2). HIV-1 is related to viruses found in chimpanzees and gorillas living in western Africa, while HIV-2 viruses are related to viruses found in sooty mangabeys. HIV-1 viruses may be further divided into groups. The HIV-1 group M viruses predominate and are responsible for the AIDS pandemic. Group M can be further subdivided into subtypes based on genetic sequence data. Some of the subtypes are known to be more virulent or are resistant to different medications. Likewise, HIV-2 viruses are thought to be less virulent and transmissible than HIV-1 M group viruses, although HIV-2 is known to cause AIDS.
Keywords
HIV-2 Envelope 201 Antigen; Retroviridae; Lentivirus; Human immunodeficiency virus 2; HIV-2 Envelope 201 Antigen; HIV-2

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