HIV type 1 TAT (DAG-P2905)

HIV type 1 TAT (full length), recombinant protein from E. coli Datasheet

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Product Overview
HIV1 tat full length protein
Nature
Recombinant
Tag/Conjugate
Unconjugated
Cellular Localization
Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
Bio-activity
HIV1 tat full length protein reacts with anti-Tat antibodies from human, monkey, rabbit and mouse serum.
Purity
> 90 % by SDS-PAGE.
Format
Lyophilised
Buffer
Preservative: None Constituents: 0.1% Glycerol
Storage
Store at -70°C Preservative: None Constituents: 0.1% Glycerol
Reconstitution
The protein should be reconstituted in apirogenic sterile water or PBS buffer. The reconstituted solution has to be used immediately.
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
Antigen Description
HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
Keywords
p14; Protein Tat; Transactivating regulatory protein; HIV1 tat

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