HIV type 1 TAT (full length), recombinant protein from E. coli
HIV1 tat full length protein
Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
HIV1 tat full length protein reacts with anti-Tat antibodies from human, monkey, rabbit and mouse serum.
> 90 % by SDS-PAGE.
Preservative: None Constituents: 0.1% Glycerol
Store at -70°C Preservative: None Constituents: 0.1% Glycerol
The protein should be reconstituted in apirogenic sterile water or PBS buffer. The reconstituted solution has to be used immediately.
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
p14; Protein Tat; Transactivating regulatory protein; HIV1 tat