HIV type 1 Protease protein (aa 25 - 127), recombinant protein from E. coli
HIV1 Protease full length protein
Km=15.1μM, Kcat = 30s-1, Kcat/Km= 1981 mM-1s-1 with peptide substrate KARVF(NO2)VRKA (F(NO2) ... p-nitrophenylalanine).
pH: 5.00Constituents: 0.01% DTT, 0.03% EDTA, 10% Glycerol, 1.17% Sodium chloride
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles. pH: 5.00Constituents: 0.01% DTT, 0.03% EDTA, 10% Glycerol, 1.17% Sodium chloride
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
A protease (also termed peptidase or proteinase) is any enzyme that performs proteolysis, that is, begins protein catabolism by hydrolysis of the peptide bonds that link amino acids together in the polypeptide chain forming the protein. Proteases have evolved multiple times, and different classes of protease can perform the same reaction by completely different catalytic mechanisms. Proteases can be found in animals, plants, bacteria, archea and viruses.
HIV-1 protease; HIV1 Protease