HIV type 1, 2 Envelope protein (DAG-P2624)

HIV type 1, 2 Envelope protein, recombinant protein from E. coli Datasheet

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Product Overview
HIV1 + HIV2 envelope antigen protein fragment
Nature
Recombinant
Tag/Conjugate
Unconjugated
Bio-activity
Detects all HIV1,2 infected individuals responding to HIV1,2 envelope proteins.
Format
Liquid
Buffer
Preservative: 0.01% Sodium Azide Constituents: 50% Glycerol, 1.5M Urea, 25mM Tris HCl, 1mM EDTA
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. Preservative: 0.01% Sodium Azide Constituents: 50% Glycerol, 1.5M Urea, 25mM Tris HCl, 1mM EDTA
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
Antigen Description
Inhibitors targeting HIV1 viral envelope proteins are used as antiretroviral drugs. The surface protein gp120 attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. The transmembrane protein gp41 acts as a class I viral fusion protein.
Keywords
Envelope glycoprotein gp160; Glycoprotein 120; Glycoprotein 41; gp120; gp41; HIV1 + HIV2 envelope antigen

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