HIV type 1 gp41 Antigen, Coating [ENV126-J] (DAGA-361)
HIV type 1 gp41 Antigen [ENV126-J], Recombinant antigen
Datasheet
Nature
Recombinant
Tag/Conjugate
TBD
Molecular Weight
16 KD
Alternative Names
env; Glycoprotein 41; gp41; TM; Transmembrane protein; HIV gp41 L
Application Notes
Paired with cat# DAGA-362
Purity
>90%
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements.
Size
1 mg
Buffer
250mM Glycine +25mM Tris-HCl +1/K SDS
Storage
Store at 2-8°C and at -20°C for long-term storage. Don't repeated freeze-thaw
Antigen Description
gp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
Keywords
env;Glycoprotein 41;gp41;TM;Transmembrane protein;HIV gp41 L;HIV type 1 gp41;HIV-1 gp41
Citations
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