HIV type 1 Glycoprotein 120 (DAG-P2443)

HIV type 1 Glycoprotein 120 (aa 27 - 498), recombinant protein from HEK 293 cells Datasheet

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Product Overview
HIV-1 gp120 (Du172.17 full length protein
Nature
Recombinant
Tag/Conjugate
Unconjugated
Molecular Weight
54 kDa including tags
Cellular Localization
Cell Membrane
Purity
> 97 % by SDS-PAGE.
Format
Lyophilised
Buffer
pH: 7.40Constituent: 99% PBSNote: Normally Mannitol or Trehalose are added as protectants before lyophilization
Storage
Store at +4°C. Aliquot and store at -20°C or -80°C when reconstituted. Avoid repeated freeze / thaw cycles. pH: 7.40Constituent: 99% PBSNote: Normally Mannitol or Trehalose are added as protectants before lyophilization
Reconstitution
It is recommended to reconstitute the lyophilized protein in 10μl sterile deionized water to a final concentration of 1mg/ml. Solubilize for 30 to 60 minutes at room temperature with occasional gentle mixing. Carrier protein (0.1% HSA or BSA) is strongly
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
Antigen Description
The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
Keywords
gp120; gp120 glycoprotein; Human Immunodeficiency Virus 1; SU; Surface protein; HIV-1 gp120

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