HHV-4 p18 (DAGA-612)

HHV-4 p18, recombinant protein from E. coli

Alternative Names
Herpesviridae; p18; Lymphocryptovirus p18; Human herpesvirus 4 (HHV-4); p18
>95% by SDS-PAGE
Batch dependent - please inquire should you have specific requirements
25mM Tris-HCl, 1,5 M urea, 50% glycerol
Protein is shipped at ambient temperature. Upon arrival, Store at -20°C
Antigen Description
E.coli derived recombinant. The mosaic protein contains the HHV-4 p18 regions
Herpesviridae;p18;Lymphocryptovirus p18;Human herpesvirus 4 (HHV-4);p18


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The association between Epstein-Barr virus and oral lichen planus: A systematic review and meta-analysis


Authors: Ashraf, Sajna; Al-Maweri, Sadeq A.; Alaizari, Nader; Umair, Ayesha; Ariffin, Zaihan; Alhajj, Mohammed N.; Kassim, Saba; Awan, Kamran Habib

Background Oral lichen planus (OLP) is a relatively common inflammatory disease, with unclear etiology. A number of studies have linked Epstein-Barr virus (EBV) with OLP. The present systematic review and meta-analysis aimed to evaluate the available evidence regarding the potential association between EBV and OLP. Methods Online databases (PubMed, Scopus, Web of Science, ProQuest, and Google Scholar) were searched from date of inception till May 2020. Studies were included if they met the following criteria: 1) observational studies that assessed the relationship between EBV and OLP, 2) the study comprised OLP patients and control subjects, 3) diagnosis of OLP was confirmed histopathologically, and 4) articles were in English. Studies without control groups, experimental studies, case reports, and reviews were excluded. The fixed-effects model was performed for meta-analyses using RevMan 5.3 software. Results A total of 10 studies comprising 386 OLP cases and 304 controls were included. Of these, only 8 studies were eligible for the meta-analysis. The results of the quality assessment showed that only 2 studies were of high quality, while the remaining studies were of moderate quality. The results of the pooled eight studies revealed a significant positive association between EBV and OLP (OR = 4.41, 95% CI: [2.74, 7.11],P < .0001). Conclusion The results of the present systematic review suggest that EBV infection is statistically associated with increased risk of OLP. However, these results are preliminary, and high-quality, large-scale studies are warranted to further explore the potential role of EBV in the pathogenesis of OLP.

Indolent EBV-positive T-cell lymphoproliferative disorder arising in a chronic pericardial hematoma: the T-cell counterpart of fibrin-associated diffuse large B-cell lymphoma?


Authors: Wang, Zhen; Gong, Qixing; Zhao, Youcai; Xu, Hai; Hu, Shimin; Zhang, Zhihong

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