Human HCK ELISA Matched Antibody Pair (ABPR-0415)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Species Reactivity
Human
Intended Use
This antibody pair set comes with matched antibody pair to detect and quantify protein level of human HCK.
General Description
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Reconstitution And Storage
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.

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References


Pozzobon, M; Marafioti, T; et al. Intracellular signalling molecules as immunohistochemical markers of normal and neoplastic human leucocytes in routine biopsy samples. BRITISH JOURNAL OF HAEMATOLOGY 124:519-533(2004).
Kumar, P; Hosaka, S; et al. Soluble E-selectin induces monocyte chemotaxis through Src family tyrosine kinases. JOURNAL OF BIOLOGICAL CHEMISTRY 276:21039-21045(2001).

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