Human GRIK5 blocking peptide (CDBP1434)

Synthetic Human GRIK5 blocking peptide for BL

Product Overview
Blocking peptide for anti-Grik5 antibody
Target
Grik5
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.
Function
PDZ domain binding; SH3 domain binding; extracellular-glutamate-gated ion channel activity; identical protein binding; ion channel activity; kainate selective glutamate receptor activity; receptor activity;
Synonyms
GRIK5; glutamate receptor, ionotropic, kainate 5; GRIK2; glutamate receptor, ionotropic kainate 5; GluK5; KA2; glutamate receptor KA2; glutamate receptor KA-2; excitatory amino acid receptor 2; EAA2;

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References


SZPIRER, C; MOLNE, M; et al. THE GENES ENCODING THE GLUTAMATE-RECEPTOR SUBUNITS KA1 AND KA2 (GRIK4 AND GRIK5) ARE LOCATED ON SEPARATE CHROMOSOMES IN HUMAN, MOUSE, AND RAT. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 91:11849-11853(1994).
Yosifova, A; Mushiroda, T; et al. Genome-wide association study on bipolar disorder in the Bulgarian population. GENES BRAIN AND BEHAVIOR 10:789-797(2011).

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