Monoclonal anti-idiotype antibodies are ideal for preclinical research (PK, Tox and immunogenicity study) and the generation of data to support the development of antibody drugs. Creative Diagnostics has developed high-quality monoclonal anti-idiotypic antibodies used in sandwich ELISA for quantification of drug antibodies in patient serum.
Our monoclonal anti-idiotype antibody solution is a highly customizable service based entirely on the customer needs. To complement the monoclonal anti-idiotype antibodies development, we offer following feature services:
| Item | Basic Package | Peptide Package | Fab & F(ab)2 Package |
|---|---|---|---|
| Experimental scheme design (1-2 days) | √ | √ | √ |
| Peptide synthesis up to 20 aa, HPLC purity > 90% (3-4 weeks) | √ | ||
| Peptide conjugation to carrier protein (KLH, BSA, OVA) | √ | ||
| Fab & F(ab)2 fragmentation and purification (3-4 weeks) | √ | ||
Phase I: Immunization (4-6 weeks)
| √ | √ | √ |
Phase II: Fusion (2-3 weeks)
| √ | √ | √ |
Phase III: Sub-cloning (4-6 weeks)
| √ | √ | √ |
| Isotyping of final clones | √ | √ | √ |
Antibody production (3-4 weeks)
| √ | √ | √ |
Please contact us to understand more custom monoclonal anti-Idiotypic antibodies production services from Creative Diagnostics to meet your specific requirements.
