HSV type 2 Glycoprotein D (DAG4305)

HSV type 2 Glycoprotein D, recombinant protein from E. coli Datasheet

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Product Overview
Recombinant Herpes Simplex Virus-2 gD
Specificity
Immunoreactive with sera of HSV-infected individuals.
Nature
Recombinant
Tag/Conjugate
Unconjugated
Purity
Protein is > 95% pure as determined by 10% PAGE (coomassie staining).
Concentration
1mg/ml in 25mM Tris-HCl, 1mM EDTA, and 50% glycerol.
Storage
2-8°C short term, -20°C long term
Introduction
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family, Herpesviridae, that infect humans. Both HSV-1 (which produces most cold sores) and HSV-2 (which produces most genital herpes) are ubiquitous and contagious. They can be spread when an infected person is producing and shedding the virus.
Antigen Description
Glycoprotein D(gD) binds specifically to the herpesvirus entry mediator receptor (HVEM), thus providing a strong, fixed attachment to the host cell. These interactions bring the membrane surfaces into mutual proximity and allow for other surface glycoprot
Keywords
Herpesviridae; Alphaherpesvirinae; Simplexvirus; Herpes simplex virus 1; HSV-1; Herpes simplex virus 2; HSV-2; Herpes simplex virus; HSV 1&2; Herpes Simplex Virus Type 1 & 2; HSV1 + HSV2 gD; Envelope glycoprotein D; GD; Glycoprotein D; US6

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