HIV type 1 HIV-1 gp120 [GST], recombinant protein from E. coli
Recombinant Human HIV-1 gp120, GST-tagged
Immunoreactive with sera of HIV-infected individuals.
> 95%, as determined by SDS-PAGE.
Lyophilized from 20mM PBS pH-7.8, 20mM NaCl 0.5M, 1mM DTT 8M urea.
2-8°C short term, -20°C long term
Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. The four major routes of transmission are unsafe sex, contaminated needles, breast milk, and transmission from an infected mother to her baby at birth (perinatal transmission). Screening of blood products for HIV has largely eliminated transmission through blood transfusions or infected blood products in the developed world.
gp120 is a glycoprotein exposed on the surface of the HIV envelope.The glycoprotein gp120 is anchored to the viral membrane, or envelope, via non-covalent bonds with the transmembrane glycoprotein, gp41. It is involved in entry into cells by binding to CD
HIV-1 gp120; HIV1 gp120; Envelope surface glycoprotein gp120; Glycoprotein 120; gp120; gp120 glycoprotein; Human Immunodeficiency Virus 1; SU; Surface protein; Retroviridae; Lentivirus; human immunodeficiency virus