Specifications
Immunogen
Des-acyl ghrelin (synthetic)
Target
Alternative Names
ghrelin/obestatin prepropeptide; MTLRP; ghrelin, growth hormone secretagogue receptor ligand; Growth hormone-releasing peptide; Motilin-related peptide; Growth hormone secretagogue; ghrelin; obestatin; appetite-regulating hormone; GHRL; ghrelin/obestatin
Product Background
Antigen Description
Ghrelin is a hormone produced mainly by P/D1 cells lining the fundus of the human stomach and epsilon cells of the pancreas that stimulates hunger. Ghrelin levels increase before meals and decrease after meals. It is considered the counterpart of the hormone leptin, produced by adipose tissue, which induces satiation when present at higher levels. In some bariatric procedures, the level of ghrelin is reduced in patients, thus causing satiation before it would normally occur.
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem; Synthesis, Secretion, and Deacylation of Ghrelin, organism-specific biosystem
Citations
Publication ()
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COA
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