Chicken Growth Hormone 1 (DAG3432)

Chicken Growth Hormone 1, recombinant protein from E. coli

Product Overview
Recombinant Chicken Growth Hormone 1
Nature
Recombinant
Tag/Conjugate
Unconjugated
Procedure
None
Purity
Greater than 99.0% as determined by:(a) Analysis by SDS-PAGE gel. (b) Analysis by SEC-HPLC.
Format
Sterile Filtered White lyophilized (freeze-dried) powder. The protein was lyophilized from a concentrated (1 mg/ml) solution with 0.3% NaHCO 3 adjusted to pH 8.
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Antigen Description
GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same
Keywords
GH; IGHD1B; GH-N; Somatotropin; GHN; Growth hormone; hGH-N; GH1; HGH

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