Human GEMIN6 ELISA Matched Antibody Pair (ABPR-0375)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Species Reactivity
Human
Intended Use
This antibody pair set comes with matched antibody pair to detect and quantify protein level of human GEMIN6.
General Description
GEMIN6 is part of a large macromolecular complex, localized to both the cytoplasm and the nucleus, that plays a role in the cytoplasmic assembly of small nuclear ribonucleoproteins (snRNPs). Other members of this complex include SMN (MIM 600354), GEMIN2 (SIP1; MIM 602595), GEMIN3 (DDX20; MIM 606168), GEMIN4 (MIM 606969), and GEMIN5 (MIM 607005).[supplied by OMIM, Jul 2002]
Reconstitution And Storage
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.

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References


Carissimi, C; Saieva, L; et al. Gemin8 is required for the architecture and function of the survival motor neuron complex. JOURNAL OF BIOLOGICAL CHEMISTRY 281:37009-37016(2006).
Todd, AG; Morse, R; et al. Analysis of SMN-neurite granules: Core Cajal body components are absent from SMN-cytoplasmic complexes. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 397:479-485(2010).

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