Human FBXW2 blocking peptide (CDBP1212)

Synthetic Human FBXW2 blocking peptide for Apuri, BL, ELISA Datasheet

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Product Overview
Blocking/Immunizing peptide for anti-FBXW2 antibody
Target
FBXW2
Nature
Synthetic
Species Reactivity
Human, Mouse
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Size
100 μg
Storage
Shipped at ambient temperature, store at -20°C.
UniProt ID
Antigen Description
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
Function
ubiquitin-protein ligase activity;
Synonyms
FBXW2; F-box and WD repeat domain containing 2; F box and WD 40 domain protein 2; F-box/WD repeat-containing protein 2; FBW2; Fwd2; Md6; F-box and WD-40 domain protein 2; F-box and WD-40 domain-containing protein 2; MGC117371;

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