This gene encodes a member of a family of proteins that are characterized by an F-box motif. The encoded protein also contains leucine-rich repeats. F-box-containing proteins comprise one of the subunits of the SCF (SKP1-cullin-F-box) complex, which functions in phosphorylation-dependent ubiquitination. Alternative splicing results in multiple transcript variants.
Function
ubiquitin-protein ligase activity;
Synonyms
FBXL6; F-box and leucine-rich repeat protein 6; F-box/LRR-repeat protein 6; FBL6; F-box protein Fbl6; FBL6A; PP14630;
Citations
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