E. coli Formamidopyrimidine-DNA glycosylase (DAG-P2307)

E. coli Formamidopyrimidine-DNA glycosylase (aa 1 - 269), recombinant protein from E. coli Datasheet

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Product Overview
E. coli Formamidopyrimidine-DNA glycosylase full length protein
Nature
Recombinant
Tag/Conjugate
Unconjugated
Molecular Weight
30 kDa
Purity
>95% by SDS-PAGE .Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Format
Liquid
Buffer
pH: 7.80Constituents: 0.02% DTT, 0.32% Tris HCl, 0.03% EDTA, 50% Glycerol, 0.58% Sodium chloride
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. pH: 7.80Constituents: 0.02% DTT, 0.32% Tris HCl, 0.03% EDTA, 50% Glycerol, 0.58% Sodium chloride
Introduction
Escherichia coli; commonly abbreviated E. coli) is a gram-negative, facultatively anaerobic, rod-shaped bacterium of the genus Escherichia that is commonly found in the lower intestine of warm-blooded organisms (endotherms). Most E. coli strains are harml
Antigen Description
Formamidopyrimidine-DNA glycosylase is a DNA glycosylase that releases damaged bases preferentially from duplex DNA. It has an associated class I AP (apurinic/apyrimidinic) lyase activity. Fpg Cleaves the DNA backbone to generate a single-strand break at the site of the removed base, The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving 3' and 5' phosphoryl groups.
Keywords
AP Lyase MutM; DNA (Apurinic or Apyrimidinic Site) Lyase MutM; Fapy DNA; Glycosylase; fpg; mutM; E. coli Formamidopyrimidine-DNA glycosylase; Escherichia coli Formamidopyrimidine-DNA glycosylase

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