Dihydrotestosterone [HRP] (DAG1092)

Dihydrotestosterone, HRP-conjugated, synthetic

Product Overview
Dihydrotestosterone, HRP conjugate
Target
DHT
Nature
Synthetic
Tag/Conjugate
HRP
Procedure
None
Format
Concentrate
Size
0.5 mL
Preservative
None
Storage
2-8°C short term, -20°C long term
Warnings
PLEASE note that this product is intended for research use only; not for diagnostic or clinical use.
Introduction
Dihydrotestosterone is a hormone that stimulates the development of male characteristics (an androgen). It is made through conversion of the more commonly known androgen, testosterone. Almost 10% of the testosterone produced by an adult each day is converted by the testes and prostate (in men), the ovaries (in women), the skin and other parts of the body to dihydrotestosterone.
Antigen Description
Dihydrotestosterone is a biologically active metabolite of the hormone testosterone, formed primarily in the prostate gland, testes, hair follicles, and adrenal glands by the enzyme 5a-reductase by means of reducing the 4,5 double-bond. Dihydrotestosterone is produced by males in utero and is responsible for the formation of male gender-specific characteristics as well as contributing to other characteristics generally attributed to males, including facial and body hair growth, and deepening of the voice.
Keywords
Dihydrotestosterone; DHT; 5a-dihydrotestosterone; 5a-DHT; Androstanolone; 5a-androstan-17b-ol-3-one; 17b-hydroxy-5a-androstan-3-one

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References


Levine, AC; Liu, XH; et al. Androgenic effects on prostate specific antigen secretion by human fetal prostate are mediated by keratinocyte growth factor. MOLECULAR UROLOGY 2:65-71(1998).
DeAngeli, S; Favretti, C; et al. Effects of DHT and EGF on human hyperplastic prostate cells cultured in vitro: Growth, morphology and phenotype characterisation. ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER 179:255-264(1997).

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