Digoxin [FITC] (DAG172)

Product Overview
Digoxin is a glycoside extracted from the foxglove plant Digitalis lanata. Purification by preparative thin-layer chromatography(TLC).
Target
Digoxin
Nature
Synthetic
Tag/Conjugate
FITC
Bio-activity
1450 units/ml - One unit of activity is defined as the amount of enzyme causing the hydrolysis of one micromole of p-nitrophenyl phosphate per minute of 25 degree C and pH 9.6.
Procedure
None
Format
Liquid
Size
1 mL
Buffer
8mM Tris, 0.9% NaCI, 0.1% NaN3, 0.1% MgCl2.
Preservative
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Storage
Store at 4°C.
Warnings
PLEASE note that this product is intended for research use only; not for diagnostic or clinical use.
Introduction
Digoxin is a beta blocker drug originally derived from the foxglove plant, Digitalis lanata. Digoxin is used primarily to improve the pumping ability of the heart in congestive heart failure (CHF), and treat problems such as high blood pressure. It is also used to help normalize some dysrhythmias (abnormal types of heartbeat).
Keywords
Digitalis; Lanoxin; Digoxin

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References


Liu, LZ; Jiang, ST; et al. Direct detection of microRNA-126 at a femtomolar level using a glassy carbon electrode modified with chitosan, graphene sheets, and a poly(amidoamine) dendrimer composite with gold and silver nanoclusters. MICROCHIMICA ACTA 182:77-84(2015).
Chan, BSH; Buckley, NA; et al. Digoxin-specific antibody fragments in the treatment of digoxin toxicity. CLINICAL TOXICOLOGY 52:824-836(2014).

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