DHX36 blocking peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

Format

Liquid

Concentration

200 μg/mL

Preservative

None

Storage

-20°C

Entrez Gene ID

Antigen Description

This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Function

ATP binding; ATP-dependent helicase activity; DNA-dependent ATPase activity; G-quadruplex DNA binding; G-quadruplex RNA binding; core promoter binding; double-stranded RNA binding; histone deacetylase binding; poly(A) RNA binding; protein binding; transcription regulatory region DNA binding

Synonyms

DHX36; DEAH (Asp-Glu-Ala-His) box polypeptide 36; G4R1; RHAU; DDX36; MLEL1; ATP-dependent RNA helicase DHX36; G4 resolvase-1; G4-resolvase 1; MLE-like protein 1; DEAH box protein 36; probable ATP-dependent RNA helicase DHX36; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36; RNA helicase associated with AU-rich element ARE