Human NR0B1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-DAX1/NR0B1 antibody

Target

DAX1 / NR0B1

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Gene ID

190

UniProt ID

P51843

Antigen Description

This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq, Jul 2008]

Function

AF-2 domain binding; DNA binding; DNA hairpin binding; RNA binding; double-stranded DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; ligand-activated sequence-specific DNA binding RNA polymerase

Synonyms

NR0B1; nuclear receptor subfamily 0, group B, member 1; AHC, dosage sensitive sex reversal , DSS; nuclear receptor subfamily 0 group B member 1; AHCH; DAX1; nuclear receptor DAX1; nuclear receptor DAX-1; nuclear hormone receptor; DSS-AHC critical region on the X chromosome protein 1; AHC; AHX; DSS; GTD; HHG; DAX-1; NROB1; SRXY2;