Human DAD1 blocking peptide (CDBP0955)

Synthetic Human DAD1 blocking peptide for BL

Product Overview
Blocking peptide for anti-DAD1 antibody
Target
DAD1
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.
Function
contributes_to dolichyl-diphosphooligosaccharide-protein glycotransferase activity; contributes_to oligosaccharyl transferase activity; transferase activity;
Synonyms
DAD1; defender against cell death 1; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; oligosaccharyltransferase 2 homolog (S. cerevisiae); OST2; DAD-1; oligosaccharyltransferase 2 homolog; oligosaccharyl transferase subunit DAD1;

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References


Mishra, R; Leahy, P; et al. Gene expression profile of endothelin-1-induced growth in glomerular mesangial cells. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 285:C1109-C1115(2003).
Druz, A; Son, YJ; et al. Stable inhibition of mmu-miR-466h-5p improves apoptosis resistance and protein production in CHO cells. METABOLIC ENGINEERING 16:87-94(2013).

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