Human COL7A1 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-Collagen, type VII antibody

Target

Collagen, type VII

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008]

Function

identical protein binding; protein binding; serine-type endopeptidase inhibitor activity;

Synonyms

COL7A1; collagen, type VII, alpha 1; EBD1; EBR1; EBDCT; collagen alpha-1(VII) chain; LC collagen; long-chain collagen; collagen VII, alpha-1 polypeptide;