Clostridium tetani Tetanus Toxoid (DAGA-115)

Clostridium tetani Tetanus Toxoid, native protein Datasheet

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Product Overview
Activity: Maximum T cell stimulation observed at 1 ug/mL.
Structure: Two subunits, one heavy chain of 100 kD and a light chain of 50 kD joined by a disulfide bond.
Nature
Native
Tag/Conjugate
Unconjugated
Molecular Weight
150 kD
Alternative Names
Tetanus Toxoid; Clostridium tetani toxoid; Tentoxylysin; Tetanus toxin; tetX; Clostridium tetani Tetanus Toxoid protein
Procedure
None
Concentration
Batch dependent - please inquire should you have specific requirements.
Size
100 micrograms
Preservative
None
Storage
Store at 2-8oC. Mix well just before use
Antigen Description
Tetanus toxoid is an inactivated form of tetanus toxin. Tetanus toxin is an exotoxin produced by Clostridium tetani and is the agent responsible for "lockjaw". Tetanus toxin binds to presynaptic membranes and is internalized by nerves. The toxin is then transported to the central nervous system through retrograde axonal transport within the neuron. In the CNS, the toxin blocks neurotransmitter release leading to the muscle spasms characteristic of tetanus.
Keywords
Tetanus Toxoid; Clostridium tetani toxoid; Tentoxylysin; Tetanus toxin; tetX; Clostridium tetani Tetanus Toxoid protein; C. tetani Tetanus Toxoid protein

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