Chikungunya Virus IgG capture ELISA Kit (DEIA6128)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Size
96T
Sample
serum
Species Reactivity
Human
Intended Use
The Chikungunya IgG-ELISA is intended for the qualitative determination of IgG class antibodies to Chikungunya in human serum.
Contents of Kit
1. Chikungunya Microplate (IgG)
2. Sample Diluent
3. Stop Solution
4. Washing Solution (20X conc.)
5. Chikungunya Solution 1
6. Chikungunya Solution 2
7. Streptavidin conjugate
8. TMB Substrate Solution
9. Chikungunya IgG Positive Control
10. Chikungunya IgG Cut-off Control
11. Chikungunya IgG Negative Control
Storage
The reagents are stable up to the expiry date stated on the label when stored at 2-8°C. For more detailed information, please download the following document on our website.
Sensitivity
The diagnostic sensitivity is >90%.

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References


High proportion of Guillain-Barre syndrome associated with chikungunya in Northeast Brazil

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION

Authors: Brasil Matos, Aline de Moura; Maia Carvalho, Fernanda Martins; Malta, Danielle Lima; Rodrigues, Cleonisio Leite; Felix, Alvina Clara; Pannuti, Claudio Sergio; da Rocha Lima, Amanda Dias; Alves Esposito, Danilo Lucas; Barbosa dos Santos, Leonilda Maria; von Glehn, Felipe; Baima Colares, Jeova Keny; Lopes da Fonseca, Benedito Antonio; Penalva de Oliveira, Augusto Cesar; Romano, Camila Malta

From 2013 to 2015, sanitary authorities reported an increased incidence of Guillain-Barre syndrome (GBS) associated with Zika virus (ZIKV) in French Polynesia, Caribbean, and Brazil.(1-3) After the end of ZIKV epidemics, GBS cases where still above the usual limits in countries where the arrival of chikungunya virus (CHIKV) was also a concern.(3) Here, we report the findings from Hospital Geral de Fortaleza (HGF), a neuroinvasive arboviral disease vigilance center in Ceara State, Northeast Brazil.

Chikungunya resurgence in the Maldives and risk for importation via tourists to Europe in 2019-2020: A GeoSentinel case series

TRAVEL MEDICINE AND INFECTIOUS DISEASE

Authors: Dudouet, Pierre; Gautret, Philippe; Larsen, Carsten Schade; Diaz-Menendez, Marta; Trigo, Elena; von Sonnenburg, Frank; Gobbi, Federico; Grobusch, Martin P.; Malvy, Denis; Field, Vanessa; Asgeirsson, Hilmir; Souto, Ines Oliveira; Hamer, Davidson H.; Parola, Philippe; Javelle, Emilie

Background: Chikungunya virus (CHIKV) is an arthropod-borne virus mainly transmitted in tropical areas by Aedes spp. mosquitoes. It has been responsible for small-to-large outbreaks in temperate areas including southern Europe and North America. Past outbreaks in 2006 on the islands of Maldives, as well as on other islands in the Indian Ocean and in Southeast Asia, demonstrated for the first time the capacity of CHIKV to disseminate through travel and transcontinental commerce, and revealed the major socio-economic impact of CHIKV epidemics. Recently, CHIKV has been circulating in highly touristic areas including the Maldives, where 1736 cases were notified by the Health Protection Agency during 2019. Case series: Among EuroTravNet/GeoSentinel patient records, eight CHIKV-confirmed cases imported the Maldives to France, Germany, Denmark, Italy and Spain were identified between February 2019 and February 2020; exceeding the total number of CHIKV infections travel-acquired in Maldives reported to this surveillance network during the previous 10 years. Conclusions: The prevention and control of CHIKV introduction into naive areas colonised by competent vectors is crucial. CHIKV outbreaks must be detected and reported in a timely manner. This must lead to adapted health information for international travellers and to prompt management of suspected imported cases. Conversely, travellers make for excellent sentinels and increased reports of imported cases might reflect a change in the level of endemicity or even herald an outbreak. Feedback to the local health authorities and matching this with local epidemiological surveillance data may lead to health benefits for the local population.

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