Mouse anti-Human CSNK1D monoclonal antibody for WB, IHC, IF, sELISA, ELISA
CSNK1D (Casein Kinase 1 Delta) is a Protein Coding gene. Diseases associated with CSNK1D include advanced sleep-phase syndrome, familial, 2 and advanced sleep phase syndrome. Among its related pathways are Gene Expression and Transport to the Golgi and subsequent modification. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CSNK1G2. This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for this gene.
Advanced sleep phase syndrome, familial, 2 (FASPS2) [MIM:615224]: A disorder characterized by very early sleep onset and offset. Individuals are morning larks with a 4 hours advance of the sleep, temperature and melatonin rhythms. Note=The disease is caused by mutations affecting the gene represented in this entry. The CSNK1D gene encodes the casein kinase I isoform delta enzyme in humans. 0The function about CSNK1D antigen include ATP binding; nucleotide binding; protein binding; protein kinase activity; protein kinase activity; protein kinase activity; protein serine/threonine kinase activity; tau-protein kinase activity.
Canonical Wnt signaling pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian rhythm - mammal, organism-specific biosystem; Circadian rhythm - mammal, conserved biosystem.
Kannanayakal, TJ; Tao, HY; et al. Casein kinase-1 isoforms differentially associate with neurofibrillary and granulovacuolar degeneration lesions. ACTA NEUROPATHOLOGICA 111:413-421(2006).
Shanware, NP; Hutchinson, JA; et al. Casein Kinase 1-dependent Phosphorylation of Familial Advanced Sleep Phase Syndrome-associated Residues Controls PERIOD 2 Stability. JOURNAL OF BIOLOGICAL CHEMISTRY 286:-(2011).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.