Anti-CLEC2D monoclonal antibody (DMABT-H13445)

Mouse anti-Human CLEC2D monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
5D8
Species Reactivity
Human
Immunogen
CLEC2D (AAH19883,2a.a. ~265a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
CLEC2D; C-type lectin domain family 2, member D; C type lectin superfamily 2, member D; C-type lectin domain family 2 member D; C type lectin related f; CLAX
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CLEC2D (C-Type Lectin Domain Family 2 Member D) is a Protein Coding gene. Among its related pathways are Immune System and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. GO annotations related to this gene include transmembrane signaling receptor activity and carbohydrate binding. An important paralog of this gene is CLEC2L. This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene.
Antigen Description
Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans. C-type lectin domain family 2 member D is a protein that in humans is encoded by the CLEC2D gene. 0The function about CLEC2D antigen include binding; receptor activity; sugar binding; transmembrane signaling receptor activity.

Citations


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References


Juul-Madsen, HR; Munch, M; et al. Serum levels of mannan-binding lectin in chickens prior to and during experimental infection with avian infectious bronchitis virus. POULTRY SCIENCE 82:235-241(2003).

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