Anti-CES2 monoclonal antibody (DMABT-H13417)

Mouse anti-Human CES2 monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
5G23
Species Reactivity
Human
Immunogen
CES2 (NP_003860, 514 a.a. ~ 621 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
CES2; carboxylesterase 2; carboxylesterase 2 (intestine, liver); cocaine esterase; CE 2; CES2A1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; E2F transcription factor network, organism-specific biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Irinotecan Pathway, organism-specific biosystem;

Citations


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References


Higuchi, R; Fukami, T; et al. Prilocaine- and Lidocaine-Induced Methemoglobinemia Is Caused by Human Carboxylesterase-, CYP2E1-, and CYP3A4-Mediated Metabolic Activation. DRUG METABOLISM AND DISPOSITION 41:1220-1230(2013).
Furihata, T; Hosokawa, M; et al. Purification, molecular cloning, and functional expression of inducible liver acylcarnitine hydrolase in C57BL/6 mouse, belonging to the carboxylesterase multigene family. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 416:101-109(2003).

Custom Antibody Labeling


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