The MIF2 homology domain II targets centromeres and binds the alpha satellite DNA in vivo. The MIF2 homology domain III can induce CENPC dimerization/oligomerization.
Format
Liquid
Preservative
None
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12. [provided by RefSeq, Jul 2008]
Function
DNA binding; centromeric DNA binding;
Synonyms
CENPC; centromere protein C; MIF2; hcp-4; CENP-C; CENPC1; CENP-C 1; centromere protein C 1; centromere autoantigen C; centromere autoantigen C1; interphase centromere complex protein 7;
Citations
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