Purified from bovine thymus. After coating onto ELISA plates the product will bind autoantibodies to Ro (SSA).
RO; CRT; SSA; cC1qR
The Ro autoantigen (60 kDa) is more than 90% pure, as assessed by SDS polyacrylamide gel electrophoresis.
The product is stabilised with 0.1% Micr-O-protect TM. Store at -20°C or below (long term) or at +4°C (short term). Avoid repeated freezing and thawing. Mix thoroughly before use.
Calreticulin also known as calregulin, CRP55, CaBP3, calsequestrin-like protein, and endoplasmic reticulum resident protein 60 (ERp60) is a protein that in humans is encoded by the CALR gene.
Calreticulin is a multifunctional protein that binds Ca2+ ions (a second messenger in signal transduction), rendering it inactive. The Ca2+ is bound with low affinity, but high capacity, and can be released on a signal (see inositol triphosphate). Calreticulin is located in storage compartments associated with the endoplasmic reticulum.
The term "Mobilferrin" is considered to be the same as calreticulin by some sources.
CALR;Calreticulin;Ro (SSA) Antigen;SSA Antigen;Ro Antigen;