Human C5 peptide

Background Physicians can find it challenging to decide whether confirmative digital subtraction angiography (DSA) should be performed in patients who present with "suspicious small aneurysm-like structures" on magnetic resonance angiography (MRA). Factors associated with "false positive aneurysms on MRA" (FPAMs)," which are finally confirmed as negative on DSA, have rarely been reported. This study aimed to identify the clinical or radiologic clues indicative of FPAM on DSA. Methods Patients who had undergone DSA between 2016 and 2019 for suspicious aneurysm-like structures < 5 mm in size on MRA were enrolled. Patient demographics and the details regarding the geometry of the structures were retrospectively reviewed. Univariate and multivariate logistic regression analyses were conducted to identify the associated factors. Receiver operating characteristic curve analysis was performed to assess the clinical implications. Results Of the 107 suspicious structures, 46 were indicated as being false positive on DSA (42.96%). Location (positive on C7 and negative on C5-6 ICA) and lower dome to neck ratio were found to be significant parameters in the multivariate analysis. The dome to neck ratio threshold value was 0.99. Conclusion Suspicious aneurysm-like structures located not on C5-6 but on C7 ICA and having wide neck morphologies (dome to neck ratio < 0.99) are highly likely to be negative on DSA.

Purpose Environmental sustainability has become a primary factor for organisations to compete globally. Stakeholders' involvement with necessary commitment at the right stage of supply chain management (SCM) plays a vital role in development of green supply chain. This paper aims to explore the involvement aspect of stakeholders towards greening of the supply chain. The purpose of this paper is to identify the critical success factors for stakeholder involvement in development of green supply chain and develop use cases for managers and practitioners planning to implement recent technologies to support stakeholders' involvement. Design/methodology/approach After a thorough literature survey and interviews with experts from industry and academia, the factors for involvement of stakeholders for greening the supply chain were identified. A survey-based research has been used to collect primary data for effective people involvement in development of green supply chain. The decision-making trial and evaluation laboratory method is used for ranking the critical success factors. Effective implementation of success factors using merits of blockchain and internet of things (IoT) technologies are discussed. Use cases are developed for practitioners for using a blockchain IoT-integrated architecture. Findings The results show that criterion C21 (cooperation with buyer for green initiatives) is the most important for green supply chain, and criterion C5 (global customers) has least effect on greening the supply chain. Involving stakeholders in the green product design ensures improved efficiency of the supply chain. Merits of technologies like blockchain and IoT may be reaped successfully for incorporating critical success factors to develop green supply chain. Research limitations/implications The research can further be extended by developing the research model with hypothesis and conducting a survey for validation. Automobile industry use cases are considered for this research, and it may be further developed for different industry sectors like process industries, service, etc. Practical implications Managers can make use of these 22 critical success factors and capabilities of the blockchain IoT-integrated architecture to successfully involve stakeholders. Practitioners/managers can dramatically change SCM with respect to the response speed, accuracy of decision-making, data acquisition, data storage and data accessibility, transparency, trust-building, opportunity of participation, communication quality, freedom in payment based on blockchain IoT-integrated architecture. Preventing pollution and converting the enterprises into green and sustainable organisations have created lot of concerns worldwide. This research addresses the issue of green initiatives and the role of stakeholders in improving the green status of industry. Originality/value Though there is research on involving suppliers and customers in the supply chain activities, there is a significant delay in integrating human resource management in the supply chain. This research proposes integration of stakeholders using recent technologies for green supply chain. Use cases developed for the automobile industry gives path to future research in this domain.